Quicklists
public 01:34:52

Math Slam! : TBA

  -   Graduate/Faculty Seminar ( 114 Views )

public 01:14:39

Lucy Zhang : Modeling and Simulations of Fluid and Deformable-Structure Interactions in Bio-Mechanical Systems

  -   Applied Math and Analysis ( 154 Views )

Fluid-structure interactions exist in many aspects of our daily lives. Some biomedical engineering examples are blood flowing through a blood vessel and blood pumping in the heart. Fluid interacting with moving or deformable structures poses more numerical challenges for its complexity in dealing with transient and simultaneous interactions between the fluid and solid domains. To obtain stable, effective, and accurate solutions is not trivial. Traditional methods that are available in commercial software often generate numerical instabilities.

In this talk, a novel numerical solution technique, Immersed Finite Element Method (IFEM), is introduced for solving complex fluid-structure interaction problems in various engineering fields. The fluid and solid domains are fully coupled, thus yield accurate and stable solutions. The variables in the two domains are interpolated via a delta function that enables the use of non-uniform grids in the fluid domain, which allows the use of arbitrary geometry shapes and boundary conditions. This method extends the capabilities and flexibilities in solving various biomedical, traditional mechanical, and aerospace engineering problems with detailed and realistic mechanics analysis. Verification problems will be shown to validate the accuracy and effectiveness of this numerical approach. Several biomechanical problems will be presented: 1) blood flow in the left atrium and left atrial appendage which is the main source of blood in patients with atrial fibrillation. The function of the appendage is determined through fluid-structure interaction analysis, 2) examine blood cell and cell interactions under different flow shear rates. The formation of the cell aggregates can be predicted when given a physiologic shear rate.

public 01:24:58

Ju Sun : When Are Nonconvex Optimization Problems Not Scary?

  -   Applied Math and Analysis ( 143 Views )

Many problems arising from scientific and engineering applications can be naturally formulated as optimization problems, most of which are nonconvex. For nonconvex problems, obtaining a local minimizer is computationally hard in theory, never mind the global minimizer. In practice, however, simple numerical methods often work surprisingly well in finding high-quality solutions for specific problems at hand.

In this talk, I will describe our recent effort in bridging the mysterious theory-practice gap for nonconvex optimization. I will highlight a family of nonconvex problems that can be solved to global optimality using simple numerical methods, independent of initialization. This family has the characteristic global structure that (1) all local minimizers are global, and (2) all saddle points have directional negative curvatures. Problems lying in this family cover various applications across machine learning, signal processing, scientific imaging, and more. I will focus on two examples we worked out: learning sparsifying bases for massive data and recovery of complex signals from phaseless measurements. In both examples, the benign global structure allows us to derive geometric insights and computational results that are inaccessible from previous methods. In contrast, alternative approaches to solving nonconvex problems often entail either expensive convex relaxation (e.g., solving large-scale semidefinite programs) or delicate problem-specific initializations.

Completing and enriching this framework is an active research endeavor that is being undertaken by several research communities. At the end of the talk, I will discuss open problems to be tackled to move forward.

public 01:34:49

Xiantao Li : The Mori-Zwanzig formalism for the reduction of complex dynamics models

  -   Applied Math and Analysis ( 120 Views )

Mathematical models of complex physical processes often involve large number of degrees of freedom as well as events occurring on different time scales. Therefore, direct simulations based on these models face tremendous challenge. This focus of this talk is on the Mori-Zwanzig (MZ) projection formalism for reducing the dimension of a complex dynamical system. The goal is to mathematically derive a reduced model with much fewer variables, while still able to capture the essential properties of the system. In many cases, this formalism also eliminates fast modes and makes it possible to explore events over longer time scales. The models that are directly derived from the MZ projection are typically too abstract to be practically implemented. We will first discuss cases where the model can be simplified to generalized Langevin equations (GLE). Furthermore, we introduce systematic numerical approximations to the GLE, in which the fluctuation-dissipation theorem (FDT) is automatically satisfied. More importantly, these approximations lead to a hierarchy of reduced models with increasing accuracy, which would also be useful for an adaptive model refinement (AMR). Examples, including the NLS, atomistic models of materials defects, and molecular models of proteins, will be presented to illustrate the potential applications of the methods.