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Kirill B. Skouibine : The Role of Cardiac Tissue Structure in Reentry Induction: A Modeling Study

Most dangerous cardiac arrhythmia, ventricular fibrillation (VF), is characterized by chaotic electrical behavior of the tissue. At the onset of the first, more organized stage of VF waves of electric activity in the heart become reentrant leading to fast irregular contraction. Better understanding of the mechanisms underlying early VF events will lead to more efficient treatment. Reentry induction has been performed in several experiments. We devise a model of cardiac tissue and use it to obtain a close match to the experimental results. The model combines macroscopic and microscopic properties of cardiac tissue.

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