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Rodica Curtu : Mixed-Mode Activity Patterns in Neuronal Networks with Lateral Inhibition

Stimulus tuning in a reduced model for neural competition leads to mixed-mode oscillations (MMOs), a temporal pattern featuring alternating small- and large-amplitude oscillations. Key ingredients for the generation of MMOs are mutual inhibition, slow negative-feedback in the form of adaptation, and nonlinearity of the gain function. Exploiting a normal form calculation, we show that MMOs occur due to the interaction of canard and singular Hopf mechanisms as the stimulus strength approaches a critical regime. We show then that local excitation and lateral inhibition-type coupling combined with the underlying MMOs produces complex spatio-temporal patterns in larger networks.

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