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Jay Newby : Spontaneous neural activity from stochastic ion channels (Oct 2, 2014 4:20 PM)
How does intrinsic noise from stochastic ion channels affect spontaneous activity in a single neuron? The size of a neuron affects how many ion channels in the membrane facilitate the generation of action potentials. Fewer ion channels causes an increase in the number of spontaneous action potentials. The density of neural tissue is therefore fundamentally limited by spontaneous activity. Evolutionary pressure tends to favor neural tissue with higher density for a variety of reasons, but the increase in spontaneous activity limits how dense it can become and still remain functional. I will talk about how large deviation theory can be used to quantify the relationship between ion channels (type and number) and spontaneous activity.
- Category: Probability
- Duration: 01:49:45
- Date: October 2, 2014 at 4:20 PM
- Views: 110
- Tags: seminar, Probability Seminar
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