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Alun Lloyd : Drug Resistance in Acute Viral Infections

A wide range of viral infections, such as HIV or influenza, can now be treated using antiviral drugs. Since viruses can evolve rapidly, the emergence and spread of drug resistant virus strains is a major concern. We shall describe within and between host models that can help indicate settings in which resistance is more or less likely to be problematic. In particular, we shall discuss the potential for the emergence of resistance in the context of human rhinovirus infection, an acute infection that is responsible for a large fraction of 'common cold' cases.

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