Cecilia Clementi : A multiscale approach to characterize macromolecular dynamics and functions
A multiscale approach to characterize macromolecular dynamics and functions The understanding of emerging collective behaviors in biomolecular complexes represents a major challenge in modern biophysics. As a first step toward the study of such processes we have applied multi-resolution nonlinear dimensionality reduction and diffusion analysis to obtain reliable low-dimensional representations and models for the dynamics of apparently high-dimensional complex systems such as proteins in a biological environment. The results clearly show that the proposed methods can efficiently find low dimensional representations of a complex process such as protein folding.
- Category: Mathematical Biology
- Duration: 01:14:51
- Date: February 3, 2012 at 11:55 AM
- Tags: seminar, Mathematical Biology Seminar