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L. Mahadevan : Mechanochemistry and motility: individual and collective behavior

I will describe three different types of problems inspired by the dynamics of the cytoskeleton: (i) the structural and kinetic aspects of dynamic instability in macromolecular assemblies, (ii) the collective flagella-like dynamics of ordered assemblies of active particles and cells, and (iii) the onset of oscillations and the persistence of strain in disordered aggregates of motors and filaments. In all cases, I will show how simple aspects of geometry, chemical kinetics and statistical and continuum mechanics allow us to explain biological observations in a minimal setting.

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